If so, share your PPT presentation slides online with PowerShow.com. It's FREE! giuseppe biondi zoccai, md department of medico-surgical, Cerebral Venous Thrombosis - . The three factors include: venous stasis, activation of blood coagulation, and vein damage. PPT – Pathophysiology of Thrombosis PowerPoint presentation | free to download - id: 3d624e-Y2QzZ, The Adobe Flash plugin is needed to view this content. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. Learn about the symptoms and treatment of this condition. And, best of all, most of its cool features are free and easy to use. In brief, SARS-CoV-2 consists of four main structural glycoproteins: spike (S), membrane (M), envelope (E), and nucleocapsid (N). Thrombosis. by: dr. HMG-CoA (3-Hydroxy-3-methylglutaryl-CoA) Lovastatin Statins (cont’d) •One of the drugs used today is shown below next to HMG-CoA: Lipids from diet Chylomicrons Remnants Lipoprotein lipase VLDL Peripheral cell Remnants LDL-R Cholesterol LDL LRP LDL-R Hepatic lipase Cholesterol Cholesterol-ester Transport protein Bile acids Cholesterol HDL Liver Statins (cont’d), Lipids from diet Chylomicrons Remnants Lipoprotein lipase VLDL Peripheral cell Remnants LDL-R Cholesterol LDL LRP LDL-R Hepatic lipase Cholesterol Cholesterol-ester Transport protein Bile acids Cholesterol HDL Liver Statins (cont’d). Displaying pathogenesis of thrombosis PowerPoint Presentations Thrombosis Judoctors PPT Presentation Summary : The propagating portion of a thrombus is poorly attached ... blood (can potentially distinguish antemortem thrombosis from postmortem clots) postmortem blood •Atherosclerosis narrows arteries, a process that causes ischemia, infarction, and necrosis. Examples of Atherosclerosis of Human Arteries The degree of atherosclerosis is much greater in this coronary artery, and the lumen is narrowed by half. 3. Deep vein thrombosis (DVT) occurs when a blood clot (thrombus) forms in one or more of the deep veins in your body, usually in your legs. Pathophysiology. - Increase in tissue mass that results from the excess ... Gene on chromosome 21 carries gene for amyloid protein ... May revolve around amyloid protein ... - General Principles of Pathophysiology Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... Pathophysiology of vascular tone. J Thromb Haemost 2010; 8: 1886–94. Many of them are also animated. D., M D. Nataliya Potikha Regulation of arterial pressure ( P) CO leads to PR and P ... - Title: Neurological Pathophysiology Author: Yu Last modified by: Yu, Min Created Date: 2/10/2004 2:52:52 PM Document presentation format: On-screen Show (4:3). Examples of Atherosclerosis of Human Arteries Microscopically, the aortic atheromatous plaque is thicker than the remaining media at the right. “Response-to-Injury Hypothesis” for Development of Atherosclerosis 4. Clinically, the role of vessel wall damage in the pathogenesis of venous thrombosis is uncertain at this time, but immobility plus increased coagulability is recognized as a major risk factor. •Hepatitis — fatigue, sluggishness, anorexia, and weight loss — resemble those of an influenza-like syndrome. Condition. Although named after Virchow, a German doctor and early pioneer of thrombosis research in the 1850’s, what is now known as Virchow’s triad … - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. - SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. Pathogenesis of Thrombosis. "National Research Council. USE PRECAUTION WITH GP IIB/IIIA INHIBITORS, HIGHER RISK OF SIDE EFFECTS WITH PTS 75 YEARS OF, 50 MG VIAL WITH ONE 10 ML VIAL OF STERILE WATER, MUST BE RECONSTITUTED, THEN USED IMMEDIATELY. By: Dr. Malak El-Hazmi Dr. Abdulkarim Alhetheel - Introduction to medical virology “ viral pathogenesis”. - VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY Blood Flow Blood vessels = arteries, veins Three tissue layers (inside to outside) Intima Epithelium + connective ... Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial. Thrombus formation and propagation depend on the presence of abnormalities of blood flow, blood vessel wall, and blood clotting components, known collectively as Virchow's triad. Retinal vein occlusion (RVO) is the most common •The most effective way to prevent arterial thrombosis is to prevent the underlying atherosclerosis. symptoms . Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. Atherosclerosis •No disease in the U.S. is responsible for more deaths and has engendered more controversy than atherosclerosis (AS). Rudolf Virchow. •Depending upon the nature and duration of the insult, the protective response may become excessive and over many years in its excess become a disease process. Clearance of activated coagulation factors by the liver; 6. causes. •Atherosclerosis affects large and medium-sized arteries. Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are acute thrombotic microangiopathies (TMAs) characterized by acute episodes of intravascular hemolysis, thrombocytopenia and microvascular thrombosis leading to end‐organ damage becoming apparent as acute kidney injury, cerebrovascular accidents or seizures, and myocardial … Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. This can lead to a buildup of fatty material (called plaque) in the artery walls. Arterial hypertension. Virchow's triad (venous stasis, vessel wall injury, and hypercoagulability) summarizes the mechanisms by which acquired and inherited risk factors (Table 10‐1) predispose to VTE.Typically, lower‐extremity thrombus develops in valve pockets of the calf veins. Management and Prevention •Antithrombotic medication now forms an important part of the management and prevention of: -ischemic heart disease (IHD); -stroke; -and other vascular conditions. fibrin, hemorrhage, hemostatic function, hemostatics, intravital microscopy, thromboplastin, thrombosis, thrombus, cardiovascular system, host defense The hemostatic process is a host defense mechanism—nature’s effort to preserve the … •Inverse relationship between symptomatic AS and high-density lipoprotein (HDL or HDL-C) levels. Arterial hypertension Ph. Genetics. outline. •Virchow's triad (1845) postulated that thrombosis results from alterations in vessel wall, blood flow, and properties of blood. These cells adhere to the endothelium and invade the artery wall. A small area of calcification is seen in the plaque at the right. •Lowering LDL-C helps prevent and may even reverse atherosclerosis, and it may even decrease the risk of heart attacks and strokes: -statins -bile acid-binding resins -niacin -fibrates. The dominant influence, and the one factor that by itself can lead to thrombosis, is endothelial injury.2,5,6 Endothelial Injury: Endothelial injury causes subendothelial collagen exposure and platelet adherence, among other changes; many factors can contribute to the injury, including hypertension, vasculitis, scarred valves, bacterial endotoxins, cholesterolemia, and chemicals … 1865: Molecular pathogenesis of subarachnoid haemorrhage - . •Statins lower serum LDL-C concentrations by up-regulating LDL-receptor activity and by reducing entry of LDL into the circulation. basic skeletal structures & functions. dr.roaa h. gadeer md. Thrombus nearly occluding the lumen of the carotid artery. tibial veins, soleal/gastrocnemius veins. Neutralization of activated coagulation factors by endothelial cell-bound components; 3. ( 1) mechanisms on placental cell ( i ) thrombosis ( a), Deep Vein Thrombosis (DVT) - . Thrombus may form on top of such a plaque. •Hypertension is a major risk factor for atherosclerosis and may well be more important than hypercholesterolemia after age 45. 1969. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. Viral Pathogenesis - . doi: 10.17226/20259. Pathogenesis :- Endothelial injury – platelets adhere to subendothelial collagen Platelets secretes ADP and thromboxane A2 Plateles expose phospholipid complex – activates intrinsic coagulation pathway Tissue factor from injured endothelium – activates extrinsic coagulation pathway ADP – reversible primary hemostatic plug ADP, thrombin, TXA2 – irreversible secondary plug Fibrin … Risk Factors •Prevalence and severity of the disease are related to many factors, some constitutional but others are acquired and potentially controllable. It can result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity. Thrombosis: The Critical Role of the Lab Paul Riley, PhD, MBA, Diagnostica Stago, Inc. Learning Objectives Describe the basic pathophysiology of DIC Demonstrate a diagnostic and management approach for DIC Compare markers of thrombin & plasmin generation in DIC, including D-Dimer, 72, 87-90 In addition, anticoagulation for arterial events and atrial fibrillation may be required. × Inappropriate thrombus formation is a disruption of homeostasis and may result from an alteration in any of the factors listed below. - Bern-Rotterdam Registry Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large ... Clinical Pathophysiology Of Cardiovascular Diseases. thrombus formation in deep veins of legs or thighs. Arterial thrombosis is often associated with atherosclerosis. Pathophysiology of DVT Virchow’s triad was developed to help identify the factors that were present in those patients who were developing DVTs. jørn dalsgaard nielsen thrombosis centre gentofte hospital denmark. **the signs and, Normal Bone Growth and the Pathogenesis of Osteoporosis - . Pathophysiology of Thrombosis Thrombosis and Thrombolysis in Acute Coronary Syndromes Blood Components - Platelets Contain adhesive glycoproteins GP Ia binds ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3d624e-Y2QzZ Here is occlusive coronary atherosclerosis. Thrombotic events, including venous thrombosis and portal vein thrombosis are frequent in patients with cirrhosis. blood components - platelets. To view this presentation, you'll need to allow Flash. Atherosclerosis (cont’d) •It is a disease of the arterial intima leading to the formation of fibrous (“atheromatous”) plaques- proliferation of smooth muscle cells and the accumulation of lipids. 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